Cardio Drugs and Dementia; Fampridine and Working Memory; Alzheimer’s and Cancer
Long-term use of many common cardiovascular drugs was tied to fewer dementia diagnoses but anti-platelet use of any duration was associated with higher dementia risk, Swedish data showed. (Alzheimer’s & Dementia)
Repeated intake of fampridine (Fampyra), a potassium channel blocker used to improve walking in multiple sclerosis (MS), led to higher working memory performance in low-performing adults. (Molecular Psychiatry)
Pre-existing MS should not preclude using immune checkpoint inhibitors for cancer in older patients, a retrospective analysis of immune-related adverse events suggested. (Neurology)
Artificial intelligence (AI) identified three presenting phenotypes of Chiari type-1 malformation and syringomyelia. (Neurosurgery)
How might AI-enabled medical devices affect neurology prognoses? (JAMA Neurology)
Interim data from a phase II study showed that investigational ACI-7104.056 induced high anti-alpha-synuclein antibody levels in early Parkinson’s disease, AC Immune said.
Rest tremor was correlated with dopamine levels preserved in the caudate nucleus. (npj Parkinson’s Disease)
Researchers proposed hospital care standards to avoid preventable harms to Parkinson’s patients. (Joint Commission Journal on Quality and Patient Safety)
The FDA expanded the age indication for the Nerivio migraine treatment device to include pediatric patients, Theranica announced.
The agency also authorized icometrix’s AI-driven MRI software to detect and grade amyloid-related imaging abnormalities (ARIA) in Alzheimer’s patients treated with amyloid-targeting therapies.
Investigational gantenerumab trial data showed that ARIA with edema had no long-term effect on cognitive performance in most early Alzheimer’s participants. (JAMA Neurology)
Compared with no treatment, systemic dexamethasone was associated with improved survival free of cerebral palsy when bronchopulmonary dysplasia risk was greater than 70%. (JAMA Pediatrics)
Why are cancer survivors less likely to develop Alzheimer’s? (The Guardian)
AARP said it’s partnering with two health organizations to help identify dementia risk factors.
